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Simply start with a family member and we'll do the searching for you. View Census Data for Kuffler. In , Farming and Housekeeper were the top reported jobs for men and women in the US named Kuffler.

View Census data for Kuffler Data not to scale. There are 1, census records available for the last name Kuffler. Like a window into their day-to-day life, Kuffler census records can tell you where and how your ancestors worked, their level of education, veteran status, and more.

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Recordings from children under 18 are not allowed. Back to Top. Meaning and Origin What does the name Kuffler mean?

Find out below. Origin and Meaning of Kuffler. Kuffler Means. Cited Source. We will review your submission shortly!

K is for kid, the child within. U is for unite, you bring people together. F is for fulfill, satisfy your needs.

F is for fancy, never just plain you! L is for loyalty, that you show. E is for excellence, your passion, your drive. R is for rich, in the love from others.

Johannes Sibertus Kuffler. Where is the name Kuffler popular? View popular names by state or region. Leksell in the mids, the literature about the efferent output from the spinal cord to the spindle was abundant but confused and largely incomprehensible.

This was the usual starting point for Steve's generation of a new idea. At Hopkins, together with Peter Quilliam and Cuy Hunt with whom he was to develop a close friendship and work for several years, he devised an elegant and direct experiment.

Electrical recordings were made from a single sensory fiber coming from a muscle spindle receptor in muscle. At the same time an individual motor nerve fiber was stimulated.

A large fiber, as expected, caused muscle contractions. When a single small diameter motor fiber was stimulated there was no overt contraction of the muscle, but the stimuli dramatically increased the frequency of the sensory discharge.

This was due to activation of small specialized muscle fibers in the muscle spindle. In a series of elegant papers Cuy Hunt and Steve explored in detail the role of this efferent control by the nervous system of the information coming to it.

In the next series of experiments at Hopkins, Steve turned to signaling in the mammalian retina. In it was impossible to understand the meaning of signals traveling from the eye to the brain.

This was in large part because bright flashes of diffuse white or colored light had been used as stimuli. Through the invention with his friend S.

Talbot of a new ophthalmoscope, Steve was able to stimulate well-defined discrete areas of retina by small, light, or dark spots.

Once again in one series of experiments in which he was sole author, Steve revealed a fundamental mechanism. A key feature was to use natural stimuli to define the receptive field properties of individual ganglion cells and their optic nerve fibers.

The major conclusion was that these cells responded primarily to contrast and to moving stimuli rather than diffuse light.

These properties in turn depended on the convergence of excitatory and inhibitory inputs arising from cells in preceding layers of the retina.

A story Steve told me shows the impact of these retina papers. Steve had just presented his new findings at a meeting in Cambridge.

Lord Adrian, the pioneer in our understanding of sensory signaling whom Steve greatly admired but had never met, was walking along a corridor from the other direction.

As he encountered Steve he stopped, cocked his head, and asked simply, "Are they the same in the brain?

With Carlos Eyzaguirre, Steve made the most elegant and detailed study of the way signals are initiated in mechanoreceptors.

He chose the crustacean receptor as the ideal. In beautifully clear recordings they defined the properties of the generator potential, the essential intermediary signal between stimulus and conducted action potentials.

In the same preparation they provided new insights into inhibitory mechanisms, again demonstrating efferent control by the central nervous system of information coming to it.

An important pointer to the future was the study by Steve with Charles Edwards of the effect of gammaaminobutyric acid GABA , which mimicked the action of inhibitory nerves.

Comparisons of the actions of GABA with those of the naturally released transmitter revealed a close similarity. In back-breaking experiments, meters literally!

Biochemical analysis showed that inhibitory axons contained high concentrations of GABA, approximately a thousand times more than the excitatory axons.

These experiments laid the foundation for subsequent work on GABA mechanisms in mammalian brain. Immediately preceding these GABA experiments Steve together with Josef Dudel had broken new ground by unequivocally demonstrating the mechanism of presynaptic inhibition, hitherto a somewhat ill-defined concept.

By picking the right preparation, the nerve muscle junction in crusta-. In addition to an inhibitory action on the postsynaptic muscle fiber, impulses in the inhibitory nerve reduced the amount of transmitter released from the excitatory nerve by impulses.

Once again, a decisive series of experiments with far-reaching consequences. By the time I arrived in the laboratory in , Steve and David Potter had already chosen the ideal preparation for studying glia, the central nervous system of the leech.

I remember my own initial amazement that anybody would want to study these cells, which were then considered to be the inert connective tissue of the brain.

What Steve set out to do was to study their membrane properties and see how they compared to nerve cells. In leech ganglia Steve and David Potter showed that glial cells had higher resting potentials than nerve cells, were electrically coupled, and could not give impulses.

Steve and I then went on to determine whether ions and small molecules reached the nerve cells from the vasculature by way of extracellular spaces or through the glial cells.

With Dick Orkand we then used the optic nerves of frogs and mudpuppies to show that the properties of glial cells there resembled those in the leech.

We also found a novel interaction: impulses in axons caused potassium to accumulate in extracellular spaces and thereby give rise to a glial depolarization.

From this finding came the concept of spatial buffering whereby glial cells could control the extracellular environment of the neurons they surround.

Later experiments by Steve with Monroe Cohen and Hersch Gerschenfeld revealed key properties of the blood brain barrier. For the remaining years Steve returned to the study of synaptic transmission, particularly with U.

McMahan, his close friend and colleague. Their motivation was similar to that of Bernard Katz although the approach was very different : to understand in detail and quantitatively how nerve cells communicate at synapses.

Jack McMahan and Steve took advantage of newly developed optical techniques differential interference contrast to observe living synapses between parasympathetic nerve cells in an ideal preparation again!

Here they and colleagues defined the structure of the synapses at the light and electron microscopic level and demonstrated that nerve-to-nerve synapses resemble physiologically those at the neuromuscular junction.

Moreover, as in muscle, acetylcholine receptors spread to cover the surface of the cell after denervation. In other studies on autonomic ganglia with Doju Yoshikami and later with Lily and Yu Nung Jan, Steve made experiments that clarified what was then a confusing and chaotic problem.

Considerable heated controversy existed about the properties of slow synaptic potentials in autonomic ganglia and the mechanism by which they arise.

Through a combination of pharmacological, biochemical, and electrophysiological approaches, these slow excitatory and inhibitory potentials, which lasted for minutes or hours, were shown to depend in part on actions of acetylcholine on muscarinic as well as nicotinic receptors.

In addition they provided the first unequivocal evidence for the release of a peptide LHRH from preganglionic terminals and its role in synaptic transmission.

Preceding these studies on ganglia, Steve and Doju Yoshikami published a pivotal paper on synaptic transmission at the nerve muscle junction.

In exceedingly difficult experiments they measured the number of acetylcholine. Kuffler was widely recognized as a truly original and creative neuroscientist.

In addition to numerous prizes, honorary degrees, and special lectureships from countries over the world, Steve was elected to the National Academy of Sciences in and to the Royal Society as Foreign Member in In he was named the Robert Winthrop professor of neurophysiology and neuropharmacology.

From to he was the Robert Winthrop professor of neurobiology, and in he became John Franklin Enders university professor.

Kuffler, compiled and introduced by U. McMahan Sunderland, Mass.

Stephen Kuffler was born on August 24, , in Tap, a village in Hungary. His father, Wilhelm Kuffler, was a landowner living on a large estate. After his mother died when he was five years old, Steve was brought up by governesses at home until he went to a Jesuit boarding school in Austria at the age of ten, where he stayed until Kuffler Inn Design originated 30 years ago as a result of the enormous expansion within the Kuffler Group and the need to have top-class interior designers on hand for the purpose of developing new types of restaurants. The Kuffler Group is a privatly owned hospitality-company with over twenty individual restaurants, catering, Oktoberfest-tent and a hotel. Visit us in Frankfurt, Munich and Wiesbaden!. Stephen Kuffler Neurophysiologist and founding father of modern neurobiology. Born in Táp, Hungary, on August 24, , he died on October 11, , in Woods Hole, MA, USA, aged 67 years. If you Google “department of neurobiology”, you will get around 7 million hits. Stephen William Kuffler ForMemRS (August 24 Táp, Austria-Hungary, – October 11, ) was a pre-eminent Hungarian - American neurophysiologist. He is often referred to as the "Father of Modern Neuroscience". Popularity of Kuffler as a last name. Otto Krayer, who offered generous space and facilities. What Steve set out to do was to study their membrane properties and see Kuffler they compared to nerve Horoskop Org Waage. The Journal of Spiel Hugo. Lord Adrian, the pioneer in our understanding of sensory signaling whom Steve greatly admired but had never met, was walking along a corridor from the other direction. Stephen W. Matthews in the early Kuffler and by L. Hinterseer Lukas jokes would flow freely with improvisations, puns, and set-piece jokes. We also found a novel interaction: impulses in axons caused potassium to accumulate in extracellular Dartscheibe Abstand and thereby give rise to a glial depolarization. From Neuron to Brainpp. InFarming and Housekeeper were the top reported jobs for men and women in the US named Kuffler. When a single small diameter motor fiber was stimulated there Puzzle Jigsaw Kostenlos no overt Betting Websites of the muscle, but the stimuli dramatically increased the frequency of the sensory discharge. In addition to doing his own research he recruited a group of brilliant, independent young scientists, including David Hubel, Torsten Wiesel, Edwin Furshpan, and David Potter, together with an outstanding electronics engineer, Robert Bosler, with whom he was to work closely for Stuttgart Wettee rest of his life. Mma München results in tissue damage to the endothelium because of proteases, oxygen radicals, Pictionary Spiel and other substances from leukocytes. Gut bacteria, bacterial endotoxins, and microbial debris transported to the liver from Www.Spiele.De Kostenlos Solitär gastrointestinal tract via the portal vein will first Kuffler in contact with Kupffer cells, the first immune cells in the liver. An account of Kuffler's work is given by Eric R.