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A nomenclature system has been established for antigens allergens that cause IgE-mediated atopic allergies in humans. In the event that two species names have identical designations, they are discriminated from one another by adding one or more letters as necessary to each species designation.
The allergens in this family include allergens with the following designations: Bet v 1, Dau c 1, and Pru a 1. Other proteins belonging to this family include the major pollen allergens:.
NMR analysis  has confirmed earlier predictions of the protein structure and site of the major T-cell epitope.
Four of the strands dominate the global fold, and 2 of the helices form a C-terminal amphipathic helical motif. This motif is believed to be the T-cell epitope.
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